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Premature Ovarian failure

Understanding Premature Ovarian Failure (POF)

Premature Ovarian Failure (POF), also known as Premature Ovarian Insufficiency (POI), is a condition where the ovaries stop functioning properly before the age of 40. It leads to reduced estrogen levels, irregular or absent periods, and fertility challenges. At Phular IVF Hospital, we specialize in advanced fertility care and hormone therapy to help women with POF achieve motherhood.

What is Premature Ovarian Failure?

In Premature Ovarian Failure, the ovaries lose their normal function — they stop producing eggs regularly and reduce the secretion of hormones like estrogen and progesterone. This leads to menstrual irregularities and decreased fertility, similar to early menopause, though in some cases, ovarian activity may occur intermittently.

Premature Ovarian Failure Treatment at Phular IVF

Common Symptoms

  • Irregular or missed menstrual periods
  • Hot flashes and night sweats
  • Vaginal dryness and discomfort during intercourse
  • Reduced libido
  • Fatigue, mood swings, or irritability
  • Difficulty getting pregnant

Possible Causes of POF

  • Genetic factors: Chromosomal abnormalities such as Turner’s Syndrome or Fragile X Syndrome.
  • Autoimmune disorders: The immune system attacks ovarian tissue.
  • Cancer treatments: Chemotherapy or radiation can damage ovarian follicles.
  • Environmental factors: Exposure to toxins, smoking, or certain chemicals.
  • Unknown causes: In many women, the cause remains unexplained.

Diagnosis of Premature Ovarian Failure

  • Hormonal tests: Elevated FSH and LH levels with low estrogen indicate ovarian failure.
  • AMH (Anti-Müllerian Hormone): Measures ovarian reserve and remaining egg count.
  • Ultrasound scan: Assesses the ovaries and follicle count (AFC).
  • Genetic testing: Detects chromosomal or autoimmune causes.

Impact on Fertility

Women with POF may experience infertility due to reduced egg production. However, conception is still possible through fertility treatments. Some women ovulate occasionally and can become pregnant naturally, while others may benefit from assisted reproductive techniques like IVF with donor eggs.

Treatment Options for Premature Ovarian Failure

  • Hormone Replacement Therapy (HRT): Balances estrogen and progesterone levels to manage symptoms.
  • Calcium and Vitamin D supplements: Prevent bone loss due to estrogen deficiency.
  • Lifestyle changes: Healthy diet, exercise, and stress reduction improve overall well-being.
  • Fertility Treatments:
    • IVF using donor eggs – the most effective option for pregnancy.
    • Ovulation induction in mild cases where some ovarian activity remains.
    • Egg or embryo freezing (if diagnosed early).

Phular IVF’s Approach to POF

At Phular IVF Centre, Muzaffarpur, we provide compassionate and advanced fertility solutions for women with Premature Ovarian Failure. Our team focuses on early diagnosis, hormone therapy, and assisted reproductive technologies like IVF with donor eggs to help you achieve your dream of parenthood.

Emotional & Psychological Support

A POF diagnosis can be emotionally challenging. At Phular IVF, we believe in holistic care — including emotional counseling, fertility education, and ongoing support to empower women through every step of their treatment journey.

Book Consultation for POF Treatment